Table 3 IC₅₀ values (μM) of FLLL32, curcumin, and other JAK2/STAT3 or STAT3 SH2 inhibitors in human colorectal cancer cells (C), glioblastoma cells (G), multiple myeloma (MM) and liver (L) cancer cells.

SW480 (C)

0.38

1.98

0.43

>100

86.8

10.26

HCT-116 (C)

0.32

1.51

0.96

>100

50.5

10.91

U87 (G)

0.19

5.78

0.73

55.10

>100

6.91

U251 (G)

0.26

5.04

0.84

97.30

50.70

7.10

U266 (MM)

0.48

1.38

0.99

8.87

9.50

4.76

ARH77 (MM)

2.34

3.43

2.57

35.25

28.20

10.13

SNU-449 (L)

2.04

3.85

2.50

>100

>100

9.88

SNU-398 (L)

0.65

4.88

3.23

16.20

24.30

5.37

Hep3B (L)

2.31

10.20

17.78

>100

>100

68.12

SNU-387 (L)

2.89

5.17

4.30

>100

>100

25.54