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Table 1 Response to radiotherapy according to Phillips and Verhaak classifications

From: An ANOCEF genomic and transcriptomic microarray study of the response to radiotherapy or to alkylating first-line chemotherapy in glioblastoma patients

 

Response to chemotherapy

Response to radiotherapy

Fisher's

exact test

 

No

Yes

No

Yes

 

Phillips subgroups

     

Mes.

4

7

5

6

NS

PN

2

3

6

7

NS

Proliferative

4

2

4

6

NS

Verhaak subgroups

     

Mes.

6

1

2

8

p = 0.01*

Neural

0

3

1

5

p = 0.03°

PN

3

1

4

3

NS

Classical

1

7

8

3

P = 0.02*

  1. Mes. = Mesenchymal, PN = Proneural
  2. * comparison of the frequencies of response to chemotherapy and to radiotherapy in mesenchymal and classical GBMs
  3. ° comparison of the frequency of response to treatment in neural vs. other classes of GBMs
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Molecular Cancer

ISSN: 1476-4598