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Figure 7 | Molecular Cancer

Figure 7

From: ErbB2 enhances mammary tumorigenesis, oncogene-independent recurrence and metastasis in a model of IGF-IR-mediated mammary tumorigenesis

Figure 7

ErbB2 was upregulated in metastatic tumors. Western blotting for ErbB2 and pErbB2 in primary mammary tumors from MTB-IGFIR mice that did not metastasize, primary mammary tumors that did metastasize and isolated lung metastases (a). Densitometry revealed that ErbB2 and pErbB2 levels were approximately 2-fold higher in tumors from mice with metastases (p = 0.10 for both ErbB2 and pErbB2) and approximately 3-fold higher in metastatic lesions (p = 0.09 for ErbB2 and p = 0.10 for pErbB2) compared to primary mammary tumors that did not metastasize (b).

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Molecular Cancer

ISSN: 1476-4598