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Table 1 Clinical and histological characteristics of samples (QRT-PCR analysis - 50 patients)

From: Programmed cell death 4 loss increases tumor cell invasion and is regulated by miR-21 in oral squamous cell carcinoma

Variables

N (%)

Age (years)

 

   Median (range)

67 (43-87)

Gender

 

   Male

36 (72)

   Female

14 (28)

Tobacco use

 

   Yes

38 (76)

   No

12 (24)

Alcohol use

 

   Yes

34 (68)

   No

16 (32)

Tumor Site

 

   Tongue

33 (66)

   Floor of mouth

10 (20)

   Alveolar

4 (8)

   Buccal mucosa

2 (4)

   Retromolar

1 (2)

T category

 

   T1-T2

16 (32)

   T3-T4

34 (68)

Nodal status (pathological)

 

   Negative (N0)

28 (56)

   Positive (N1, N2b, N2c)

22 (44)

Tumor Stage

 

   I-II

14 (28)

   III-IV

36 (72)

Tumor Grade

 

   Well differentiated

4 (8)

   Moderately differentiated

41 (82)

   Poorly differentiated

5 (10)

Tumor thickness (mm)

 

   Median (range)

12 (2-31)

Perineural invasion

 

   Yes

20 (40)

   No

30 (60)

Angiolymphatic invasion

 

   Yes

16 (32)

   No

34 (68)

Recurrence

 

   Yes

23 (46)

   No

27 (54)

Outcome*

 

   Alive, no evidence of disease

25 (50)

   Alive with disease

6 (12)

   Dead of disease

15 (30)

   Dead of other causes

4 (8)

  1. * last date of follow-up: October, 2009.