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Table 1 Clinical and histological characteristics of samples (QRT-PCR analysis - 50 patients)

From: Programmed cell death 4 loss increases tumor cell invasion and is regulated by miR-21 in oral squamous cell carcinoma

Variables N (%)
Age (years)  
   Median (range) 67 (43-87)
Gender  
   Male 36 (72)
   Female 14 (28)
Tobacco use  
   Yes 38 (76)
   No 12 (24)
Alcohol use  
   Yes 34 (68)
   No 16 (32)
Tumor Site  
   Tongue 33 (66)
   Floor of mouth 10 (20)
   Alveolar 4 (8)
   Buccal mucosa 2 (4)
   Retromolar 1 (2)
T category  
   T1-T2 16 (32)
   T3-T4 34 (68)
Nodal status (pathological)  
   Negative (N0) 28 (56)
   Positive (N1, N2b, N2c) 22 (44)
Tumor Stage  
   I-II 14 (28)
   III-IV 36 (72)
Tumor Grade  
   Well differentiated 4 (8)
   Moderately differentiated 41 (82)
   Poorly differentiated 5 (10)
Tumor thickness (mm)  
   Median (range) 12 (2-31)
Perineural invasion  
   Yes 20 (40)
   No 30 (60)
Angiolymphatic invasion  
   Yes 16 (32)
   No 34 (68)
Recurrence  
   Yes 23 (46)
   No 27 (54)
Outcome*  
   Alive, no evidence of disease 25 (50)
   Alive with disease 6 (12)
   Dead of disease 15 (30)
   Dead of other causes 4 (8)
  1. * last date of follow-up: October, 2009.