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Table 1 List of downregulated genes in PANC1 cells transfected with cyclin D1 or cyclin D3 siRNA.

From: Differential roles of cyclin D1 and D3 in pancreatic ductal adenocarcinoma

Cyclin D1 down regulated genes Cyclin D3 down regulated genes Common Cyclin D1 and D3 down regulated genes
Fold change with D1 siRNA Gene Symbol UniGene Fold change with D3 siRNA Gene Symbol UniGene Fold change with D1 siRNA Fold change with D3 siRNA Gene Symbol UniGene
0.1626 USP24 Hs.477009 0.3528 DHX40 Hs.29403 0.105 0.4495 SLC18A2 Hs.369009
0.2594 UHMK1 Hs.127310 0.3879 FNDC3B Hs.159430 0.3169 0.4886 TncRNA Hs.523789
0.2817 PDZD8 Hs.501149 0.3888 GPR180 Hs.439363 0.3967 0.4357 PRDX2 Hs.432121
0.3076 HIPK3 Hs.201918 0.3888 LOC144874 Hs.439363 0.4124 0.4593 LOC400043 Hs.19193
0.336 MALAT1 Hs.642877 0.3939 SLC39A6 Hs.79136 0.4233 0.4004 ELOVL6 Hs.412939
0.3422 GPR137B Hs.498160 0.405 C1orf52 Hs.26226 0.4569 0.4731 PTBP2 Hs.591430
0.3425 SIKE Hs.632428 0.4093 LIMS3 Hs.535619 0.4592 0.4352 AHNAK Hs.502756
0.3558 LIN28B Hs.23616 0.4093 LOC440895 Hs.535619 0.4615 0.4785 LOC348840 Hs.512227
0.3661 MLLT11 Hs.75823 0.4205 C14orf138 Hs.558541 0.4795 0.484 FAM70A Hs.437563
0.3673 GALNT7 Hs.127407 0.421 CYP26B1 Hs.91546 0.4798 0.4904 PPP2R1B Hs.584790
0.3739 PRMT2 Hs.154163 0.4223 GADD45B Hs.110571 0.4901 0.4935 CA5BL Hs.532326
0.3742 ARL6IP6 Hs.516468 0.4243 DBF4 Hs.485380 0.5116 0.4906 C9orf5 Hs.621479
0.3933 CNOT6 Hs.157606 0.4287 SYT11 Hs.32984     
0.3959 ATG12 Hs.264482 0.4288 SLC35F3 Hs.158748     
0.4142 WDR17 Hs.532056 0.4293 CRLF3 Hs.370168     
0.4191 PAQR3 Hs.632591 0.4334 PPP2CB Hs.491440     
0.4208 PDGFA Hs.645488 0.4361 RAB27A Hs.493512     
0.4296 LRRC58 Hs.518084 0.4433 TMEM140 Hs.567530     
0.4305 SCML1 Hs.109655 0.446 PDCD4 Hs.232543     
0.4315 RBM6 Hs.596224 0.4534 HYMAI Hs.444975     
0.4405 FAM55C Hs.130195 0.4534 PLAGL1 Hs.444975     
0.4416 CPOX Hs.476982 0.4537 ARMC8 Hs.266826     
0.4431 PGM2 Hs.23363 0.4558 IFIH1 Hs.163173     
0.446 PRPF40A Hs.591637 0.4585 SKP2 Hs.23348     
0.4463 CMTM4 Hs.643961 0.4601 AFG3L1 Hs.534773     
0.4467 FBXO27 Hs.187461 0.4607 BEX2 Hs.398989     
0.4484 HOXB8 Hs.514292 0.4612 ARL6IP5 Hs.518060     
0.4548 DLD Hs.131711 0.4614 MBOAT1 Hs.377830     
0.4554 LOC205251 Hs.128499 0.4685 SLC39A6 Hs.79136     
0.4578 LGALS8 Hs.4082 0.4731 MAP9 Hs.61271     
0.4622 E2F7 Hs.416375 0.474 GPRC5B Hs.148685     
0.4644 FAM116A Hs.91085 0.4786 GABARAPL3 Hs.592014     
0.4668 HRB Hs.591619 0.4798 C8orf44 Hs.545401     
0.468 PXK Hs.190544 0.4798 PTTG3 Hs.545401     
0.4686 CHPT1 Hs.293077 0.4798 SGK3 Hs.545401     
0.4712 USP45 Hs.143410 0.486 CDKN1A Hs.370771     
0.4718 EIF1AX Hs.522590 0.4873 SERBP1 Hs.530412     
0.4746 FDFT1 Hs.593928 0.4902 IQCK Hs.460217     
0.4762 C10orf32 Hs.34492 0.4929 DLL1 Hs.379912     
0.478 ETNK1 Hs.29464 0.4948 KDELC1 Hs.408629     
0.4823 UBE2Q1 Hs.607928 0.4959 C12orf57 Hs.591045     
0.4898 FRAT2 Hs.140720 0.4967 IFIT2 Hs.437609     
0.4918 TMEM97 Hs.199695 0.4969 BCAT1 Hs.438993     
0.4926 EML4 Hs.593614 0.4973 CUL3 Hs.372286     
0.4938 ATP11C Hs.88252 0.4992 ANP32E Hs.603000     
0.4979 TMSL8 Hs.56145 0.4998 TIA1 Hs.516075     
0.4992 PAK3 Hs.390616        
  1. Dowregulated gene targets in D-cyclin suppressed cells, unique to cyclin D1, cyclin D3, and shared targets of either D1- or D3-cyclin suppression. Genes are listed in order of ascending fold change.