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Figure 1 | Molecular Cancer

Figure 1

From: Differential expression of DKK-1 binding receptors on stromal cells and myeloma cells results in their distinct response to secreted DKK-1 in myeloma

Figure 1

Expression of DKK1 protein by human multiple myeloma cells. DKK1 protein expression was evaluated by Western blot analysis in cell lysates from HMCLs, purified CD138+ multiple myeloma cells and SCs of multiple myeloma patients. DKK-1 protein expression was obviously expressed in RPMI-8226, NCI-H929 and LP-1 and weakly expressed in U266, CZ-1 and KM-3. DKK-1 protein expression was positive in 3 of the 5 primary CD138+ myeloma cells and negative in all the SCs from 4 patients with MM. (HMCLs: RPMI-8226, U266, NCI-H929, LP-1, CZ-1, KM-3. MM1-5: freshly purified CD138+ myeloma cells of 5 MM patients. HMSC1-4: Human BM SCs from 4 MM patients)

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Molecular Cancer

ISSN: 1476-4598