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Table 1 Spots regulated within the transitions and the number of identified proteins

From: Malignant transformation in a defined genetic background: proteome changes displayed by 2D-PAGE

transition

up-regulated spots

sum of up- regulated spots

down-regulated spots

sum of down- regulated spots

sum of identified proteins

BJ → BJ-T

(hTERT)

13, 17, 20, 23

4

2, 31

2

7

BJ-T → BJ-TE

(SV40)

5, 6, 7, 8, 24*, 32

6

1, 2*, 4, 9, 10, 11, 13*, 14, 16, 18, 21, 22*, 23, 25, 26, 28, 29*, 30*, 31, 33, 38*

21

39

BJ-TE → BJ-TER

(RAS)

22*, 35

2

27*, 31*

2

8

BJ → BJ-TE

(hTERT + SV40)

5, 6, 7, 8, 17, 19, 24*, 32

8

1, 2*, 4, 9, 10, 11, 12, 13*, 14, 15, 16, 18, 22*, 23, 25, 26, 28, 29*, 30*, 31, 33, 38*, 39

23

48

BJ-T → BJ-TER

(SV40 + RAS)

3, 5, 7, 8, 19, 24*, 35, 36

8

1, 2*, 4, 9, 10, 11, 13*, 14, 16, 18, 21, 22, 23, 25, 26, 27*, 28, 29*, 30*, 31*, 38*, 39

22

47

BJ → BJ-TER

(all)

3, 5, 7, 8, 17, 19, 24*, 32, 34, 35, 36, 37

12

1, 2*, 4, 9, 10, 11, 12, 13*, 14, 15, 16, 18, 21, 22, 23, 25, 26, 27*, 28, 29*, 30*, 31*, 33, 38*, 39

25

63

  1. The numbers of spots up- or down-regulated within the transitions are listed and summed up. The number of identified proteins within regulated spots of a particular transition is presented in the right column. Spots marked with an asterisk are not detectable before or after a transition.