From: Malignant transformation in a defined genetic background: proteome changes displayed by 2D-PAGE
transition | up-regulated spots | sum of up- regulated spots | down-regulated spots | sum of down- regulated spots | sum of identified proteins |
---|---|---|---|---|---|
BJ → BJ-T (hTERT) | 13, 17, 20, 23 | 4 | 2, 31 | 2 | 7 |
BJ-T → BJ-TE (SV40) | 5, 6, 7, 8, 24*, 32 | 6 | 1, 2*, 4, 9, 10, 11, 13*, 14, 16, 18, 21, 22*, 23, 25, 26, 28, 29*, 30*, 31, 33, 38* | 21 | 39 |
BJ-TE → BJ-TER (RAS) | 22*, 35 | 2 | 27*, 31* | 2 | 8 |
BJ → BJ-TE (hTERT + SV40) | 5, 6, 7, 8, 17, 19, 24*, 32 | 8 | 1, 2*, 4, 9, 10, 11, 12, 13*, 14, 15, 16, 18, 22*, 23, 25, 26, 28, 29*, 30*, 31, 33, 38*, 39 | 23 | 48 |
BJ-T → BJ-TER (SV40 + RAS) | 3, 5, 7, 8, 19, 24*, 35, 36 | 8 | 1, 2*, 4, 9, 10, 11, 13*, 14, 16, 18, 21, 22, 23, 25, 26, 27*, 28, 29*, 30*, 31*, 38*, 39 | 22 | 47 |
BJ → BJ-TER (all) | 3, 5, 7, 8, 17, 19, 24*, 32, 34, 35, 36, 37 | 12 | 1, 2*, 4, 9, 10, 11, 12, 13*, 14, 15, 16, 18, 21, 22, 23, 25, 26, 27*, 28, 29*, 30*, 31*, 33, 38*, 39 | 25 | 63 |