Table 2 Diseases, Molecular and Cellular Functions associated with genes up-regulated (A) and down-regulated (B) by Runx2
From: Runx2 transcriptome of prostate cancer cells: insights into invasiveness and bone metastasis
A) ≥ 2 fold up-regulated, total 532 genes | p-value | genes |
|---|---|---|
   Diseases and disorders |  |  |
Cancer | 2.5e-07 - 3.0e-03 | 124 |
Genetic disorder | 5.4e-07 - 3.0e-03 | 229 |
Inflammatory response | 3.3e-06 - 2.4e-03 | 65 |
   Molecular and cellular functions |  | |
Cellular movement | 9.7e-12 - 2.5e-03 | 84 |
Cell death | 2.6e-10 - 3.2e-03 | 129 |
Cellular growth, proliferation | 9.3e-08 - 3.2e-03 | 108 |
B) ≥ 2 fold down-regulated, total 378 genes |  | |
   Diseases and disorders |  | |
Cancer | 3.3e-29 - 4.1e-03 | 124 |
Gastrointestinal disease | 3.3e-29 - 3.7e-03 | 72 |
Genetic disorder | 3.3e-06 - 3.4e-03 | 174 |
   Molecular and cellular functions |  | |
Cell cycle | 7.1e-35 - 4.1e-03 | 102 |
Cellular assembly, organization | 1.7e-18 - 3.4e-03 | 63 |
DNA replication, recombination, repair | 1.7e-18 - 4.1e-03 | 101 |