The impact of stress on tumor growth: peripheral CRF mediates tumor-promoting effects of stress

Table 1 List of genes affected by CRF

Functional groups	GenBank	Name	Symbol	Ratio control/CRF 6 h	Ratio control/CRF 24 h
1, 3, 5	NM 007614	β-Catenin	Catnb	1.43*	1.00
2, 3	NM 008284	Harvey rat sarcoma virus oncogene 1	Hras1	1.00	1.41*
2, 4	NM 008960	Phosphatase and tensin homolog	Pten	1.00	1.44*
2, 5	NM 009029	Retinoblastoma 1	Rb1	0.97	1.65*
3	NM 007484	Ras homolog gene family, member C	Rhoc	1.01	1.42*
5	NM 010754	MAD homolog 2	Smad2	2.32*	0.98
6	NM 174991	Brain-specific angiogenesis inhibitor 1	Bai1	0.44*	0.57*
2, 3	NM 134155	Breast cancer metastasis-suppressor 1	Brms1	0.60*	0.85
2, 5	NM 009870	Cyclin-dependent kinase inhibitor 2A	Cdkn2a	0.31*	0.59*

Functional groups: 1, Cell adhesion; 2, Cell cycle; 3, Cell growth and proliferation; 4, apoptosis; 5, Transcription factors and regulators; 6, Other genes involved in metastasis. *, increase or decrease equal or higher than 40%

ISSN: 1476-4598