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Figure 1 | Molecular Cancer

Figure 1

From: Frequent epigenetic inactivation of RASSF2 in thyroid cancer and functional consequences

Figure 1

Methylation of RASSFs, MSTs and WW45 in thyroid cancer cell lines. The methylation status of the indicated CpG islands was analyzed by COBRA. PCR products (for length see Additional file 5, Table S1) from bisulfite-treated DNA were digested (+) and mock digested (-) with TaqI or HpyCH4IV and resolved on 2% gel. In vitro methylated DNA (methy.) was utilized as positive control. The sizes of a 100 bp ladder (M) are indicated. Methylated (m), partially methylated (p) and unmethylated (u) samples were determined.

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Molecular Cancer

ISSN: 1476-4598