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Figure 8 | Molecular Cancer

Figure 8

From: Dasatinib reduces FAK phosphorylation increasing the effects of RPI-1 inhibition in a RET/PTC1-expressing cell line

Figure 8

Immunoblot analysis of the survival pathways. (A) Whole-cell lysates, untreated or treated with RPI-1, dasatinib, or both, and resolved by 4-12% SDS-PAGE, were analyzed by immunoblot experiments with anti-beta1 integrin and anti-phospho-SHC, -Akt, -p38MAPK, -STAT3, -ERK1/2, -FAK, and -Src.

(B) FACS analysis of TPC-1 before and after treatments showing an increase in β1-integrin surface expression.

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Molecular Cancer

ISSN: 1476-4598