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Figure 6 | Molecular Cancer

Figure 6

From: Modulation of extracellular matrix/adhesion molecule expression by BRG1 is associated with increased melanoma invasiveness

Figure 6

Down-regulation of BRG1 inhibits melanoma invasion through matrigel. A. WM-266-4 melanoma cells transfected with control (DY-547 labeled) siRNAs were visualized by phase-contrast microscopy. B. WM-266-4 melanoma cells were transfected with Acell SMART Pool siRNAs targeting BRG1 or red non-targeting siRNAs and analyzed by Western blotting. C. Control and BRG1 down-regulated WM-266-4 cells were subjected to the invasion assay as described in Figure. 5, 120 hours after transfection with siRNAs. Invasion was significantly compromised in BRG1 down-regulated cells (p < 0.01).

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Molecular Cancer

ISSN: 1476-4598