Skip to main content
Figure 2 | Molecular Cancer

Figure 2

From: Aberrant expression and constitutive activation of STAT3 in cervical carcinogenesis: implications in high-risk human papillomavirus infection

Figure 2

Increased expression and nuclear localization of STAT3 and pSTAT3 in cervical precancer and cancer lesions. Representative photomicrographs of immunohistochemical analysis of STAT3, pSTAT3(Y705) and pSTAT3(S727) in normal, precancer (LSIL & HSIL) and cancer lesions. Freshly fixed, paraffin-embedded sections (5 μm) of cervical tissues from normal, precancerous and cancerous lesion of the cervix were processed for IHC and probed for STAT3, pSTAT3(Y705) and pSTAT3(S727) with respective antibodies and detected by HRP-DAB method as described in Methods. Brown precipitate indicates immuno-positive cells, blue stain represent nuclei and co-localization of brown and blue stain represents nuclear localization of STAT3 and pSTAT3. (Original magnification: 200×)

Back to article page

Molecular Cancer

ISSN: 1476-4598