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Table 1 Significantly differentially expressed microRNAs in YSTs versus germinomas for paediatric tumours

From: The two most common histological subtypes of malignant germ cell tumour are distinguished by global microRNA profiles, associated with differential transcription factor expression

Over-expressed in YSTs

Log2 fold change

Adjusted p-value

Over-expressed in germinomas

Log2 fold change

Adjusted p-value

miR-375

3.22

2.61E-15

miR-182*

1.90

1.81E-10

miR-302a

4.17

6.61E-13

miR-146a

2.94

6.54E-08

miR-302c

4.24

1.53E-10

miR-142-5p

2.73

4.23E-07

miR-367

4.12

3.73E-10

miR-142-3p

2.97

4.23E-07

miR-302d

4.11

1.07E-09

miR-182

2.64

4.90E-07

miR-302c*

1.35

1.85E-07

miR-96

2.43

5.09E-07

miR-584

1.64

4.23E-07

miRPlus_28302

1.91

9.46E-07

miR-302b

3.49

1.02E-06

miR-146b-5p

2.26

9.46E-07

miR-205

3.25

1.78E-06

miR-155

1.84

1.02E-06

miR-638

1.21

9.52E-06

miR-29b

2.67

4.55E-06

miR-2110

0.94

1.71E-05

miR-378

1.54

8.72E-06

miR-30b*

1.15

5.28E-05

miR-30e

1.72

4.30E-05

miR-122

3.71

1.21E-04

miR-183

1.54

1.21E-04

miR-518e*

0.85

1.34E-04

miR-520b

1.65

1.21E-04

miR-572

1.21

1.84E-04

miR-29a

2.40

3.02E-04

miR-200b

2.56

3.17E-04

miR-101

1.50

3.38E-04

miRPlus_27560

1.18

3.17E-04

miR-520c-3p

1.35

3.53E-04

miR-766

0.85

3.17E-04

miR-25

1.06

4.58E-04

miR-940

0.98

5.78E-04

miR-342-3p

1.47

4.58E-04

miR-200c

2.42

6.66E-04

miR-590-5p

0.97

6.44E-04

miR-483-3p

0.84

1.47E-03

miR-526b*

1.23

7.91E-04

miR-200a

2.28

1.85E-03

miR-520g

1.44

8.73E-04

miR-455-3p

1.33

2.01E-03

miR-135b

1.66

1.50E-03

miR-296-5p

0.69

2.17E-03

miR-515-5p

1.61

1.58E-03

miR-602

0.83

2.59E-03

miR-30a

1.22

2.37E-03

miR-720

0.83

3.76E-03

miR-9

1.77

2.37E-03

miR-409-3p

1.18

5.85E-03

miR-29c*

0.78

3.64E-03

miR-210

0.74

6.36E-03

miR-29c

1.56

3.64E-03

miR-141

2.06

8.90E-03

miR-520g/h

1.13

3.76E-03

   

miR-512-3p

1.10

3.81E-03

   

let-7i

1.38

3.95E-03

   

miR-34a

1.03

4.08E-03

   

miR-340

0.68

4.87E-03

   

miR-373

1.56

5.53E-03

   

miR-515-3p

0.98

7.06E-03

   

miR-32*

0.75

8.18E-03

   

miR-151-3p

0.80

8.29E-03

  1. Analysis of the paediatric microarray data resulted in the log2 fold changes shown. microRNAs are ranked by adjusted p-value. Members of the miR-302 cluster are shown in bold.
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Molecular Cancer

ISSN: 1476-4598