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Figure 5 | Molecular Cancer

Figure 5

From: Epigenetic control of the basal-like gene expression profile via Interleukin-6 in breast cancer cells

Figure 5

Reduction of methylation at CD44 proximal promoter (CD44p) by exogenous or autocrine IL-6. Quantitative evaluation of CD44p MS-PCR analysis in: a) MCF-7 cells in presence/absence of IL-6 (10 ng/ml, 48 h) or 5azadC (15 μM, 48 h); b) pBabe/p53 D and scr/sip53 transfected (1 μg, 48 h) cells, c) p53 D cells in presence/absence of αIL-6 (1.5 μg/ml, 48 h) or transfected with scr/siIL-6 (1 μg, 48 h).

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