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Figure 2 | Molecular Cancer

Figure 2

From: Helicobacter pylori-induced activation of β-catenin involves low density lipoprotein receptor-related protein 6 and Dishevelled

Figure 2

LRP6 phosphorylation is reduced in Dvl2 and Dvl3 knockdown cell lines. NCI-N87 cells, control shRNA cells, Dvl2 shRNA cells and Dvl3 shRNA cells were infected for 1 h with H. pylori P1 wildtype strain. Membrane-enriched fractions were prepared (S-PEK Kit, Calbiochem). Western blot analysis was performed with antibodies as indicated. Diagram indicates the relative amounts of pLRP6 after densitometric analysis. Densitometric values for pLRP6 were normalised to LRP6 and TfR1 in each sample and depicted relative to the values of non-infected cells.

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