Skip to main content
Figure 3 | Molecular Cancer

Figure 3

From: Targeting the oncogenic protein beta-catenin to enhance chemotherapy outcome against solid human cancers

Figure 3

MSeA inhibition of β-catenin is due to degradation. Colorectal cancer cells were treated with a protein synthesis inhibitor, cycloheximide (CHX) and MSeA alone or in combination for various times up to 30 minutes (panel 3A) and for 24 h (panel 3B). No early changes in the β-catenin level were observed (panel 3A). However, 24 h combination treatment with CHX/MSeA resulted in same inhibition after MSeA alone (panel 3B).

Back to article page

Molecular Cancer

ISSN: 1476-4598