Figure 4From: Histone deacetylase inhibitor vorinostat suppresses the growth of uterine sarcomas in vitro and in vivoVorinostat induces apoptosis in MES-SA cells. FACS analysis of MES-SA cells labelled with cleaved caspase-3 antibody conjugated with Alexa Fluor® 488 showed an increased percentage of apoptotic cells in vorinostat-treated cells, correlating with treatment duration. MES-SA cells treated with 1 μM staurosporine for 4 hours were used as a positive control. For numerical analysis two independent experiments, each containing duplicates, were performed. Representative data are shown.Back to article page