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Figure 2 | Molecular Cancer

Figure 2

From: CD40 ligand induced cytotoxicity in carcinoma cells is enhanced by inhibition of metalloproteinase cleavage and delivery via a conditionally-replicating adenovirus

Figure 2

The effect of matrix metalloproteinase inhibitors (MPI) on RAdCD40L-induced cell death. EJ cells were infected with 100 MOI of either RAdMock (RAdM) or RAdCD40L (RAdL) or left without infection, or cultured with 1 μg/ml soluble CD40L. Twenty-four hours later cells were treated with 30 μM of MPI II or left without treatment for a further 24 hours. Cell viability was assessed by WST-1 assay. Results are the mean of triplet samples +/- SD. Two-tailed t-test RAdL vs. RAdL+MPI: p = 0.0041.

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Molecular Cancer

ISSN: 1476-4598