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Figure 1 | Molecular Cancer

Figure 1

From: Selective unresponsiveness to the inhibition of p38 MAPK activation by cAMP helps L929 fibroblastoma cells escape TNF-α-induced cell death

Figure 1

Forskolin significantly suppresses TNF-α-induced necrotic cell death in L929 fibroblastoma cells. L929 cells were pretreated with or without forskolin (FSK, 10 μM, 30 min) and then stimulated with 10 ng/ml TNF-α for 24 h or left untreated. Cell death was measured by Annexin-V/PI double staining. The percentages of cell death are shown in the lower panel as mean ± SD; n = 3. Upper panel is representative of three independent experiments. **p < 0.01.

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Molecular Cancer

ISSN: 1476-4598