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Table 1 List of extracellular matrix genes >3-fold downregulated by MFSD2A over-expression in stable-transfected A549 cells.

From: MFSD2A is a novel lung tumor suppressor gene modulating cell cycle and matrix attachment

Gene symbol Gene name Fold-change * P
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 0.25 1.13E-07
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.07 2.57E-02
COL11A1 collagen, type XI, alpha 1 0.10 2.60E-02
COL12A1 collagen, type XII, alpha 1 0.09 1.01E-03
COL4A2 collagen, type IV, alpha 2 0.25 1.78E-07
COL5A1 collagen, type V, alpha 1 0.25 1.22E-07
COL6A1 collagen, type VI, alpha 1 0.18 4.30E-03
COL7A1 collagen, type VII, alpha 1 0.25 3.60E-07
CTGF connective tissue growth factor 0.07 1.56E-08
CTNND1 catenin (cadherin-associated protein), delta 1 0.32 1.05E-02
FN1 fibronectin 1 0.16 2.53E-02
ICAM1 intercellular adhesion molecule 1 0.25 2.18E-07
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 0.18 3.52E-03
ITGA7 integrin, alpha 7 0.19 3.96E-03
LAMB3 laminin, beta 3 0.15 2.46E-02
MMP1 matrix metallopeptidase 1 (interstitial collagenase) 0.33 7.35E-03
MMP10 matrix metallopeptidase 10 (stromelysin 2) 0.27 1.84E-02
MMP14 matrix metallopeptidase 14 (membrane-inserted) 0.16 2.17E-03
MMP15 matrix metallopeptidase 15 (membrane-inserted) 0.25 3.21E-02
SELL selectin L 0.19 4.59E-03
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 0.08 1.08E-02
TGFBI transforming growth factor, beta-induced, 68 kDa 0.25 3.22E-08
THBS1 thrombospondin 1 0.19 3.82E-03
THBS3 thrombospondin 3 0.31 9.78E-03
TIMP3 TIMP metallopeptidase inhibitor 3 0.02 6.21E-05
  1. * With respect to untransfected A549 cells.