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Table 5 Cox univariate and multivariate analysis of breast cancer-specific survival in cohort II according to PKCα expression in all patients and when patients with medullary cancer are excluded.

From: PKCα expression is a marker for breast cancer aggressiveness

  All patients Medullary cancers excluded
  RR (95%CI) p value RR (95%CI) p value
  Univariate   Univariate  
PKCα negative 1.00   1.00  
PKCα positive 2.105 (1.148 to 3.862) 0.016 1.995 (1.069 to 3.721) 0.030
  Multivariate   Multivariate  
PKCα negative 1.00   1.00  
PKCα positive 2.123 (1.092 to 4.126) 0.026 1.978 (0.984 to 3.975) 0.055
  1. Multivariate analysis adjusted for Nottingham histological grade (I-II/III), age (continuous), nodal status (0/1), tumor size (continuous), and ER (< or > 10%).