Table 3 A group of highly differentially expressed genes between inflammation and cancer-associated stellate cells are shown.

DISEASE-SPECIFIC DIFFERENCES IN GENE EXPRESSION

Tumor specific transcripts (High in tumor compared to inflammation)

CELSR3 cadherin, EGF LAG seven-pass G-type receptor 3

NM_001407

3.04

SYT13 synaptotagmin XIII

NM_020826

3.04

CLCN3 chloride channel 3

NM_001829

2.69

RTN4RL1 reticulon 4 receptor-like 1

NM_178568

2.45

METAP2 methionyl aminopeptidase 2

NM_006838

2.11

PARD3 par-3 partitioning defective 3 homolog (C. elegans)

NM_019619

2.00

SYK spleen tyrosine kinase

NM_001135052

1.94

JAK2 Janus kinase 2 (a protein tyrosine kinase)

NM_004972

1.93

Inflammation specific transcripts (High in inflammation compared to tumor)

PTPRC protein tyrosine phosphatase, receptor type, C

NM_001846

2.61

DHODH dihydroorotate dehydrogenase

NM_001361

2.56

KIAA0773 KIAA0773 gene product

NM_001031690

2.38

COL4A2 collagen, type IV, alpha 2

NM_001846

2.31

PBX1 pre-B-cell leukemia transcription factor 1

NM_002585

1.70

RBP2 retinol binding protein 2, cellular

NM_004164

1.66

HPX hemopexin

NM_000613

1.64

CCL5 chemokine (C-C motif) ligand 5

NM_002985

1.63