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Figure 6 | Molecular Cancer

Figure 6

From: Prostate apoptosis response protein 4 sensitizes human colon cancer cells to chemotherapeutic 5-FU through mediation of an NFκB and microRNA network

Figure 6

Increased cytoplasmic Par-4/p65 interaction upon AKT1 inhibition in colon cancer cells. Native HT29 cells were transfected with scrambled control shRNA (scrambled) or anti-AKT1 shRNA (pshAkt1) for 48 h. Cells were triple-stained for Par-4, NFκB p65 and DAPI for confocal immunofluorescence microscopy and colocalization analysis. DAPI (blue); NFκB p65 (Alexa 488, green); Par-4 (Alexa 594, red); merge of Par-4 and p65 for colocalization (white) and DAPI staining (blue); Par-4/p65 colocalization (yellow). Arrows indicate the nuclear p65 signals in native HT29 cells.

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Molecular Cancer

ISSN: 1476-4598