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Figure 6 | Molecular Cancer

Figure 6

From: SPOCK1 as a potential cancer prognostic marker promotes the proliferation and metastasis of gallbladder cancer cells by activating the PI3K/AKT pathway

Figure 6

SPOCK1 promotes tumor invasion and metastasis in vivo by inducing EMT. (A) An in vivo metastasis assay was performed to evaluate the effect of Lv-shSPOCK1 cells on tumor metastasis. Mice that received SPOCK1-depleted NOZ cells exhibited little ascites at 4 weeks after implantation. (B) The tumor incidence rate during the 4-week observation period. (C) Immunohistochemical staining of SPOCK1, E-cadherin, and vimentin in tumor tissues of the peritoneal metastasis model.

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Molecular Cancer

ISSN: 1476-4598