Figure 5
From: Cell surface heparan sulfate proteoglycans control adhesion and invasion of breast carcinoma cells
Heparan sulfate treatment causes loss of syndecan-2 and gain of syndecan-4 on the cell surface. MDA-MB231 cells were analysed at 2, 16 and 24 h after treatment with 20 μg/ml heparan sulfate for cell surface levels of syndecans-1, −2 and −4. Control cells were untreated. FACS analysis showed decreased syndecan-2 to near background, while levels of syndecan-4 increased. Syndecan-1 levels were unchanged throughout the treatment.