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Figure 5 | Molecular Cancer

Figure 5

From: Upregulation of the inwardly rectifying potassium channel Kir2.1 (KCNJ2) modulates multidrug resistance of small-cell lung cancer under the regulation of miR-7 and the Ras/MAPK pathway

Figure 5

KCNJ2/Kir2.1 affects cell apoptosis in SCLC cells after ADM treatment. (A) Cells were analyzed by annexin-V/propidium iodide (PI) dual labeling. Representative FACS profiles are shown, on which cell population in the quadrant of Annexin V+PI−represents apoptotic cells. (B) Histographs for cell apoptosis of SCLC cells. The percentage of the Annexin V+PI−cell population was determined. The results show data from at least three independent experiments. **, P < 0.01 compared with the corresponding NC cells.

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Molecular Cancer

ISSN: 1476-4598