Table 2 Effect of KCNJ2/Kir2.1 on drug sensitivity \( \left(\overline{\mathbf{\mathsf{X}}}\pm \kern0.5em \mathbf{\mathsf{s}},\kern0.5em \mathbf{n}=\mathbf{\mathsf{3}},\kern0.5em \mathbf{\mathsf{\boldsymbol{\upmu}g}}/\mathbf{\mathsf{ml}}\right) \)

H69

5.222 ± 0.117

17.711 ± 0.279

124.03 ± 2.791

H69-NC

5.426 ± 0.87

17.548 ± 0.423

122.27 ± 2.938

H69-KCNJ2

13.678 ± 0.195*

22.649 ± 7.623*

283.41 ± 6.884*

H446

4.293 ± 0.049

4.529 ± 0.063

52.342 ± 3.0

H446-NC

4.412 ± 0.212

4.884 ± 0.068

50.296 ± 1.53

H446-KCNJ2

14.048 ± 0.242*

15.303 ± 0.712*

80.064 ± 4.97*

H69AR

211.06 ± 6.665

76.652 ± 1.238

531.58 ± 6.06

H69AR-shNC

209.69 ± 3.157

77.32 ± 1.362

529.72 ± 4.704

H69AR-shKCNJ2-1

62.275 ± 1.214*

44.583 ± 1.514*

394.74 ± 19.996*

H69AR-shKCNJ2-2

18.823 ± 0.935*

33.183 ± 2.637*

359.51 ± 8.62*

H446AR

39.29 ± 0.738

133.73 ± 4.875

179.63 ± 2.978

H446AR-shNC

42.35 ± 1.388

132.12 ± 4.434

175.64 ± 8.726

H446AR-shKCNJ2-1

27.082 ± 2.289*

72.724 ± 0.896*

118.31 ± 4.934*

H446AR-shKCNJ2-2

19.920 ± 0.688*

21.517 ± 2.693*

108.51 ± 5.772*