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Figure 4 | Molecular Cancer

Figure 4

From: RhoC is a major target of microRNA-93-5P in epithelial ovarian carcinoma tumorigenesis and progression

Figure 4

Effects of miR-93-5P transfection on ovarian carcinoma cell genotype in vitro. The predicted seed region in the 3′ UTR of RHOC showed that RHOC was a direct target of miR-93 (A); dual-luciferase reporter assay indicated that miR-93 directly targeted RHOC by binding its 3′ UTR (B). MiR-93-5P overexpression reduced RhoC, P70S6K, Bcl-xL, and MMP9 mRNA or protein expression while inducing P53 expression (C & D).

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Molecular Cancer

ISSN: 1476-4598