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Table 2 Univariate Cox proportional regression analysis on 5-year overall and disease-specific survival of 405 breast cancer patients

From: PinX1 inhibits the invasion and metastasis of human breast cancer via suppressing NF-κB/MMP-9 signaling pathway

Variable *

Overall survival

Disease-specific survival

Hazard ratio

95% CI

P *

Hazard ratio

95% CI

P *

PinX1

      

Low

1.000

 

0.012

1.000

 

0.004

High

0.573

0.371-0.884

 

0.417

0.230-0.755

 

Age

      

≤50 years

1.000

 

0.443

1.000

 

0.630

>50 years

0.864

0.594-1.225

 

0.855

0.632-1.030

 

Tumor size

      

≤5 cm

1.000

 

0.002

1.000

 

0.000

>5 cm

2.289

1.363-3.843

 

3.463

2.730-3.935

 

Lymph node metastasis

      

Negative

1.000

 

0.000

1.000

 

0.000

positive

4.994

3.032-8.227

 

3.564

2.594-4.505

 

Histology Grade

      

I

1.000

 

0.002

1.000

 

0.005

II/III

2.309

1.740-3.456

 

2.554

1.618-3.551

 
  1. * P values are from Log-rank test.
  2. CI: confidence interval.