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Table 3 Multivariate Cox regression analysis on 5-year overall and disease-specific survival of 405 breast cancer patients

From: PinX1 inhibits the invasion and metastasis of human breast cancer via suppressing NF-κB/MMP-9 signaling pathway

Variable *

Overall survival

Disease-specific survival

Hazard ratio

95% CI †

P

Hazard ratio

95% CI

P

PinX1

0.527

0.404 to 0.656

0.027

0.429

0.222 to 0.630

0.012

Age

0.993

0.740 to 1.345

0.836

0.856

0.652 to 1.222

0.884

Tumor size

2.730

1.947 to 3.785

0.003

2.913

1.882 to 4.146

0.001

Lymph node metastasis

3.183

1.911 to 4.505

0.001

3.962

2.975 to 4.756

0.000

Histology Grade

1.840

1.184 to 2.843

0.023

1.958

1.514 to 2.511

0.032

  1. *Coding of variables: PinX1 was coded as 1 (low), and 2 (high). Age was coded as 1 (≤50 years), and 2 (>50 years). Tumor size was coded as 1 (≤5 cm), and 2 (>5 cm). Lymph node metastasis was coded as 1 (negative), and 2 (positive). Histology grade was coded as 1 (I), and 2 (II and III).
  2. † CI: confidence interval.
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Molecular Cancer

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