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Figure 8 | Molecular Cancer

Figure 8

From: Preclinical analysis of the anti-tumor and anti-metastatic effects of Raf265 on colon cancer cells and CD26+ cancer stem cells in colorectal carcinoma

Figure 8

Anti-tumor effect of Raf265 in combination with 5FU. 3 weeks after inoculation of a xenograft tumor to the cecal wall of NOD/SCID mice, Raf265 was administered p.o. twice a week whereas 5FU was administered i.p. once a week for 4 weeks. Mice were sacrificed at week 4 and body weights of mice with tumors from A. HT29 and B. HCT116 cells were monitored. Representing mice with tumors from C. HT29 and D. HCT116 cells were shown in the upper panel. The average bioluminescence signals detected were also plotted and shown in the lower panel. Data are presented as means ± SD from 6 mice and statistical analysis was performed by one-way ANOVA. *p < 0.05 versus the vehicle control group with tumors from the corresponding cell lines.

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Molecular Cancer

ISSN: 1476-4598