Figure 5

Identification of differentially expressed genes between KD and non-KD cells. A: Gene expression levels for KD (22B11 and 3–4) vs. non-KD (Vec: transformed with the empty vector). The six genes in (D) are indicated. B: Genes whose expression differed by 2-fold or more between KD and non-KD (Vec.) cells. For 3–4 and 22B11 clones, 429 and 106 genes show altered expression, respectively. Among these genes, 117 showed common differential expression between 3–4 and 22B11 clones. C: A cross table of the 117 genes categorized into up or down regulation in each clone. D: Expression was enhanced for three genes (KIT, CD24, PASD1) and repressed for three genes (MS4A3, SAMSN1, MS4A4) in CCDC26-KD cells. The values were normalized against vector-transformed cells and are shown in the log2 scale. Open and filled boxes indicate enhanced and repressed expression, respectively.