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Table 1 Mass spectrometry identified O-GalNAc modified proteins

From: COSMC knockdown mediated aberrant O-glycosylation promotes oncogenic properties in pancreatic cancer

Protein Gene Uniprot acc. No. NetOGlyc 4.0 References
Nucleolin NCL P19338 +++ [35]
Alpha-1-acid glycoprotein 1 AGP1 P02763 -  
Alpha-actinin-4 ACTN4 O43707 +++  
Ig alpha-1 chain C IGHA1 P01876 ++  
Elongation factor 2 EEF2 P13639 ++  
GRP-78 HSPA5 P11021 + [33]
HSP73 HSPA8 P11142 +  
PABP1 PABPC1 P11940 ++  
PABP4 PABPC4 Q13310 +  
Alpha-enolase ENO1 Q6GMP2 +  
Elongation factor 1-gamma EEF1G P26641 ++  
EF-1-alpha-like 3 EEF1A1P5 Q5VTE0 +  
Tubulin beta TUBB2A Q13885 -  
Galectin-12 LGALS12 Q96DT0 ++  
Ras association domain-containing protein 2 RASSF2 P50749 +++  
GAPDH GAPDH P04406 +  
Nucleophosmin NPM1 Q8WTW5 +++  
Annexin A2 ANXA2 P07355 +  
37 kDa laminin receptor precursor RPSA Q86VC0 +++  
Leucyl-cystinyl aminopeptidase LNPEP Q9UIQ6 +  
eIF-5B EIF5B O60841 +++  
Armadillo repeat-containing protein 4 ARMC4 Q5T2S8 +++  
LanC-like protein 2 LANCL2 Q9NS86 ++  
  1. Proteins identified from Panc-1 COSMC knockdown cells by immunoprecipitation using VVL agarose accompanied by mass spectrometry. The O-GalNAc prediction tool (NetOGlyc 4.0) [52] was used to assess possibility of O-glycosylation. Score indicates percentage of possibly O-GalNAc modified Serin/Threonin residues (+ <10 %, ++ <20 %, +++ > 20 %). References are presented for previously identified O-GalNAc modified glycoproteins