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Table 1 Correlation between ASPP2 expression levels and clinicopathological factors in PC (n=65)

From: Downregulation of ASPP2 in pancreatic cancer cells contributes to increased resistance to gemcitabine through autophagy activation

 

No. of patients

ASPP2 expression

p-value

Low expression n=47

High expression n=18

Age (years) Mean±SD

65

54.8+13.2

59.1+11.2

0.362

Gender

Male

44

35

9

0.061

Female

21

12

9

Histopathological grade

G1

18

17

1

0.013

G2,3

47

30

17

Depth of invasion

T1, 2

41

27

14

0.133

T3, 4

24

20

4

Lymph node metastasis

Negative

33

23

10

0.639

Positive

32

24

8

Pathologic stage

I, II

59

44

15

0.203

III, IV

6

3

3

  1. Abbreviations: PC pancreatic cancer
  2. Patients with PC were divided into ASPP2 “High” group (whose density was higher than the median) and “Low” group (whose density was lower than the median). The patient and disease profiles in each group were compared
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Molecular Cancer

ISSN: 1476-4598