Table 1 P-cadherin expression in primary tumours and its relevance in malignancy. The tumour promoting or tumour suppressive effects associated with P-cadherin expression is dependent on the cellular and tissue context

Breast cancer

Up-regulation

Tumour promoting

Paredes et al., 2005 [53]

Gastric cancer

Up-regulation

Tumour promoting

Shimoyama et al., 1991 [54]

Endometrial cancer

Up-regulation

Tumour promoting

Moreno-Bueno et al., 2003 [55] Stefansson et al., 2004 [56]

Ovarian cancer

Up-regulation

Tumour promoting

Patel et al., 2003 [57]

Pancreatic cancer

Up-regulation

Tumour promoting

Taniuchi et al., 2005 [58]

Basocellular and squamous carcinoma of the skin

Up-regulation

Tumour promoting

Wakita et al.,1998 [59] Hardy et al., 2002 [60]

Cholangiocarcinoma

Up-regulation

Tumour promoting

Obama K et al., 2005 [111]

Colorectal carcinoma

Up-regulation

Tumour promoting

Hardy et al., 2002 [60] Imai et al., 2008 [9] Sun et al., 2011 [71]

Down-regulation

Tumour suppressive

Van Marck et al., 2011 [39]

Bladder cancer

Up-regulation

Tumour promoting

Wang et al., 2014 [41]

Down-regulation

Tumour suppressive

Mandeville et al., 2008 [38] Van Marck et al., 2011 [39]

Prostate cancer

Up-regulation

Tumour promoting

Arenas et al., 2000 [42]

Down-regulation

Tumour suppressive

Jarrard et al., 1997 [40]

Melanoma

Down-regulation

Tumour suppressive

Fenouille et al., 2012 [92] Van Marck et al., 2005 [43] Jacobs et al., 2011 [44]

Non small cell lung cancer

Down-regulation

Tumour suppressive

Smythe et al., 1999 [45]

Oral squamous cell carcinoma

Down-regulation

Tumour suppressive

Lo Muzio et al., 2004 [47] Muñoz-Guerra et al., 2005 [48]

Hepatocellular carcinoma

Down-regulation

Tumour suppressive

Bauer R et al., 2014 [52]