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Fig. 5 | Molecular Cancer

Fig. 5

From: miR-377-dependent BCL-xL regulation drives chemotherapeutic resistance in B-cell lymphoid malignancies

Fig. 5

High levels of BCL-xL expression in CLL patients previously treated with chemotherapy compared to those untreated. mRNA expression levels in treated and untreated CLL patients for a BCL-xL, b BCL-2, c MCL-1, d BFL-1, e BCL-W, and f BCL-B, determined by RT-PCR. Significance was determined by a t-test. RNA expression for each transcript was normalized to that obtained in lymphocytes isolated from healthy donors. Each dot represents one CLL patient

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