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Fig. 6 | Molecular Cancer

Fig. 6

From: miR-377-dependent BCL-xL regulation drives chemotherapeutic resistance in B-cell lymphoid malignancies

Fig. 6

High level of expression of BCL-xL, but not other BCL-2 family members, correlates with treatment-free survival of CLL patients. Kaplan-Meier curves for correlation of treatment-free survival in CLL patients with expression of: a BCL-xL, b BCL-2, c MCL-1, d BFL-1, e BCL-W, and f BCL-B mRNA levels were determined by RT-PCR. P values shown are for the log-rank test. RNA expression for each transcript was normalized to that obtained in lymphocytes isolated from healthy donors

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