Fig. 1
From: PKM2 regulates neural invasion of and predicts poor prognosis for human hilar cholangiocarcinoma
HK1, PKM2, and PFKB expression and its association with survival durations in patients with HC. a, HK1, PKM2, and PFKB expression in normal bile duct tissue (left panels), tumors (middle panels), and quantitative representations staining (right panels). Original magnification, ×400. b, patients with high HK1 expression had a shorter median time to recurrence than did those with low HK1 expression (12 months versus 39 months). Cum, cumulative. c, patients with high PKM2-expressing tumors had a significantly shorter median time to recurrence than did patients with low PKM2-expressing tumors (11 months versus 32 months). d, the median OS duration was significantly worse in patients with high expression of HK1 (15 months) than in those with low expression of HK1 (46 months). e, the median OS duration was significantly worse in patients with high expression of PKM2 (14 months) than in those with low expression of PKM2 (40 months)