Fig. 1
From: Minnelide effectively eliminates CD133+ side population in pancreatic cancer
a Treatment of pancreatic cancer cell lines MIA PaCa-2, S2-013 and AsPC1 with 12.5 nM triptolide for 7 days resulted in 20 % viable cells. b These cells (12 T) had increased expression of ABCG2 gene when compared to untreated CSM cells. c Increased expression of ABCG2 correlated with increased DNA dye efflux in MIA PaCa-2 12 T cells. d Quantitation of inhibition of DNA dye efflux on treatment with Verapamil, an inhibitor of ABC transporter in 12 T and CSM cells. The error bars represent SEM (n = 4; * = p < 0.05)