Fig. 2
From: Effect of low doses of actinomycin D on neuroblastoma cell lines
Role of N-Myc on the response to actinomycin D. a-c SH-EP Tet/21n cells were treated in absence (MYCN+) or in presence (MYCN−) of tetracycline with increasing doses of actinomycin D, and cell viability was measured after 24 and 48 h of treatment. IC50 was calculated at 48 h of treatment using the CalcuSyn software (Biosoft Inc.). c N-Myc protein expression was determined by Western blot analysis, 24 h after tetracycline addition