Table 2 Expression differences of selected mRNA in the validation cohort identified using qPCR
mRNA | fold change (mean) | cancer | normal | ROC analysis area under the curve | ||
|---|---|---|---|---|---|---|
mean | median | mean | median | |||
SLC6A3 | 230 | 379.006 | 335.639 | 1.645 | 0.810 | 0.955 (0.906-1.000) |
NPTX2 | 188 | 246.544 | 107.117 | 1.314 | 0.595 | 0.993 (0.982-1.000) |
TNFAIP6 | 100 | 170.493 | 60.204 | 1.701 | 0.944 | 0.980 (0.947-1.000) |
NDUFA4L2 | 78 | 104.866 | 78.748 | 1.337 | 0.861 | 0.996 (0.989-1.000) |
ENPP3 | 42 | 58.365 | 44.022 | 1.382 | 1.049 | 0.977 (0.939-1.000) |
FABP6 | 39 | 49.888 | 11.631 | 1.279 | 0.948 | 0.677 (0.555-0.800) |
SPINK13 | 26 | 51.221 | 20.516 | 1.948 | 0.939 | 0.894 (0.831-0.957) |
FXYD4 | −2371 | 0.001 | 0.000 | 2.371 | 1.179 | 0.998 (0.994-1.000) |
SLC12A1 | −912 | 0.002 | 0.000 | 1.596 | 1.352 | 1.000 (1.000-1.000) |
KNG1 | −758 | 0.002 | 0.000 | 1.602 | 1.259 | 1.000 (0.998-1.000) |
NPHS2 | −407 | 0.005 | 0.000 | 1.986 | 1.944 | 0.970 (0.936-1.000) |
SLC13A3 | −62 | 0.030 | 0.004 | 2.039 | 1.836 | 0.970 (0.943-0.997) |
GCGR | −27 | 0.047 | 0.000 | 1.291 | 1.195 | 0.983 (0.951-1.000) |
PLG | −21 | 0.113 | 0.006 | 2.406 | 1.401 | 0.927 (0.880-0.975) |