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Fig. 7 | Molecular Cancer

Fig. 7

From: Key role of MEK/ERK pathway in sustaining tumorigenicity and in vitro radioresistance of embryonal rhabdomyosarcoma stem-like cell population

Fig. 7

Effects of radiation on rhabdosphere cells and in combination with U0126. Radiation (RT) or/and 2 or 10 μM U0126 were provided after spheres formation (SC-mSPH). Samples were analyzed after 6 days. a Representative microphotographs. b Histograms of CD133 and CXCR4 positive cells determined by FACS analysis. Values represent the mean ± S.D. of 3 independent experiments (**p < 0.01, *p < 0.05). c Western blot analysis of Nanog, DNA-PKcs, Rad51 and BMX in protein lysates. Protein bands were quantified by densitometry with respect to GAPDH or α-tubulin. A representative experiment is shown

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