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Table 2 Multivariable Cox regression analysis of the 24-lncRNA risk score, LNR and postoperative chemotherapy in GSE62254 series

From: A long non-coding RNA signature to improve prognosis prediction of gastric cancer

Variables

HR

95 % CI of HR

P value

24-lncRNA risk score (N = 300)

1.16

1.10 –1.21

<0.0001

LNR

4.33

1.34 –13.93

0.014

Age

1.03

1.00 –1.05

0.032

Gender

1.10

0.65 –1.84

0.732

TNM stage I

1.00(referent)

  

TNM stage II

1.08

0.23 –5.08

0.919

TNM stage III

2.09

0.47 –9.24

0.330

TNM stage IV

3.89

0.82 –18.44

0.087

24-lncRNA risk score (N = 299)

1.14

1.09 –1.19

< 0.0001

Postoperative chemotherapy

0.36

0.18 –0.73

0.004

Age

1.01

0.99 –1.03

0.324

Gender

1.04

0.62 –1.75

0.897

TNM stage I

1.00(referent)

  

TNM stage II

1.47

0.31 –6.85

0.626

TNM stage III

4.00

0.93 –17.15

0.062

TNM stage IV

8.50

2.00 –36.20

0.004

  1. In Cox regression analysis, risk score, LNR and age were evaluated as continuous variables, and postoperative chemotherapy and gender were evaluated as category variables
  2. Abbreviations: LNR lymph node ratio, HR hazard ratio