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Fig. 8 | Molecular Cancer

Fig. 8

From: miR-4775 promotes colorectal cancer invasion and metastasis via the Smad7/TGFβ-mediated epithelial to mesenchymal transition

Fig. 8

Effects of Smad7 on miR-4775-mediated lung and liver metastases in nude mice. a–b Overexpressing or knocking down Smad7 inhibited or promoted lung metastases caused by miR-4775 upregulation or downregulation in nude mice (***p < 0.001). c–d Overexpressing or knocking down Smad7 decreased or increased the liver metastasis triggered by miR-4775 overexpression or knockdown in vivo (***p < 0.001)

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Molecular Cancer

ISSN: 1476-4598