Table 2 Colon TIC marker combinations
assessment of self-renewal | cellular system | |||||
|---|---|---|---|---|---|---|
Marker combinations | References | In vitro | In vivo | cell lines | patients | mouse |
CD166+/CD44+ | [Dalerba et al., 2007] 1 | 1✓ | 1 | |||
EpCAMhigh/CD44+ | [Dalerba et al., 2007] 1 [Kai et al., 2009] 2 | 2✓ | 1✓ 2✓ | 2 | 1 | |
CD24high/CD29+ | [Ghazvini et al., 2013] 1 | 1✓ | 1 | |||
CD133+/CD44+ | [Haraguchi et al., 2008] 1 [Chen et al., 2011] 2 | 1✓ | 1✓ 2✓ | 1 2 | 1 | |
CD133+/CD49f+ | [Haraguchi et al., 2013] 1 | 1✓ | 1 | |||
CD44+/CD49f+ | ||||||
CD24+/CD44+ | [Yeung et al., 2010] 1 | 1✓ | 1✓ | 1 | ||
CD44+/CD133− | [Wang et al., 2012] 1 | 1✓ | 1 | |||
CD133+/CD24+ | [Vermeulen et al., 2008] 1 | 1✓ | 1 | |||
CD133+/CD24- | [Vermeulen et al., 2008] 1 [Haraguchi et al., 2008] 2 | 1 − 2 − | 2 − | 2 | 1 2 | |
CD133+/CD44- | ||||||
CD133+/CD44+ | ||||||
CD133+/CD166- | ||||||
CD133+/CD166+ | ||||||
CD166+/CD44+ | [Muraro et al., 2012] 1 | 1 − | 1 − | 1 | ||
CD24+/CD44+ | ||||||
CD44+/CD166+/EpCAMlow | [Collura et al., 2013] 1 | 1 − | 1 | |||
CD44+/CD166+/EpCAMhigh | ||||||
CD133+/CD26+/CD44+ CD133+/CD26+/CD44- | [Pang et al., 2010] 1 | 1✓ | 1✓ | 1 | ||
CD133+/CD26-/CD44+ | ||||||
CD133+/CD26-/CD44- | ||||||
CD133-/CD26+/CD44+ CD133-/CD26+/CD44- | ||||||
CD133-/CD26-/CD44+ | ||||||
CD133-/CD26-/CD44- | 1 − | 1 − | 1 | |||