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Table 5 Validity estimates for miR’s promoter methylation as markers for PCa in urine samples (Cohort #3)

From: MiR-193b promoter methylation accurately detects prostate cancer in urine sediments and miR-34b/c or miR-129-2 promoter methylation define subsets of clinically aggressive tumors

microRNA

Sensitivity % (n positive/n total)

Specificity (%)

PPV (%)

NPV (%)

Accuracy (%)

miR-34b/c

89.5 (85/95)

47.8

78.0

68.8

75.9

miR-193b

91.6 (87/95)

95.7

97.8

84.6

92.9

miR-34b/c+miR-193b

90. 5% (86/95)

97.8

98.9

83.3

92.9