Table 6 Cox regression analysis assessing the potential of clinical and epigenetic variables in the prediction of disease-specific survival and disease-free survival in the Cohort #1 and Cohort #2

Variable

HR

CI (95%)

P

Variable

HR

CI (95%)

P

<7

1

≤7

1

7

3.96

1.76–8.91

0.001

>7

18.97

4.32–83.351

<0.001

>7

7.73

2.85–21.0

<0.001

≤ P75

1

<10

1

> P75

6.12

1.56–24.07

0.009

≥10

1.87

1.07–3.26

0.027

Variable

HR

CI (95%)

P

Variable

HR

CI (95%)

P

Clinical stage

Clinical stage

II

1

II

1

III/IV

9.64

2.60-35.8

<0.001

III/IV

2.57

1.18-5.60

0.018

≤ P75

1

≤ P75

1

> P75

3.84

1.27–11.6

0.017

> P75

2.76

1.24–6.15

0.013