Table 1 Bioinformatics analysis of the potential phospho sites on BMI1 protein sequence
Scorea | Sequencea | Siteb | Predicted kinase |
|---|---|---|---|
0.994 | KFLRSKMDI | S181 | PKB/ATM/Aurora/MAPK |
0.993 | LESDSGSDK | S253 | ATM/PLK1/CK2 |
0.991 | PRKSSVNGS | S316 | PKB/ATM/Aurora/IKK/CAMK/PLK1 |
0.987 | SDSGSDKAN | S255 | ATM/Aurora/CDK |
0.987 | RPRKSSVNG | S315 | ATM/Aurora/IKK/CAMK |
0.984 | DKANSPAGG | S260 | ATM/Aurora/PLK1/MAPK/CK1 |
0.955 | TPVQSPHPQ | S281 | ATM/Aurora/MAPK/CDK/CK1 |
0.951 | AANGSNEDR | S110 | ATM/CK2 |
0.918 | YLETSKYCP | S50 | ATM |