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Fig. 2 | Molecular Cancer

Fig. 2

From: Mesothelin promotes epithelial-to-mesenchymal transition and tumorigenicity of human lung cancer and mesothelioma cells

Fig. 2

MSLN knockdown reduces soft agar colony formation and tumor sphere formation. a Western blot of MSLN in several stable knockdown clones by shMSLN RNA. b Proliferation of control (shC) and MSLN knockdown (shMSLN) H2052 and H460 cells, means ± s.d. (n = 6), *P < 0.05. c Representative images and d quantification of soft agar colony formation of shC and shMSLN H2052 and H460 cells. e Representative images and f quantification of tumor sphere formation of shC and shMSLN H2052 and H460 cells. *P < 0.05 vs shC, n = 6

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